Hypertension is one of the most common medical conditions in the elderly, and antihypertensive
medications used to treat hypertension are among the most widely prescribed drugs for this age group.
The cSCC risk was not increased among users of nonphotosensitizing antihypertensives
, including alpha-blockers, beta-blockers, central agonists, and angiotensin receptor blockers.
At least one of the following enrollment criteria had to be met for inclusion in the study: (1) two or more outpatient visits within a 6-month period; (2) all prescriptions of antihypertensive
drugs continuously administered to the patients for more than 6 months within an 11-year follow-up period; or (3) one or more inpatient admissions with a diagnosis of hypertension.
In addition, tracking blood pressure twice or more per week or tracking blood glucose once or more per week was associated with significantly better adherence to antihypertensive
and oral antidiabetic medications.
Therapeutic classes were identified using the Uniform System of Classification ([dagger][dagger]) schema and included the following: angiotensin converting enzyme inhibitors and angiotensin II receptor blockers, which were assessed individually and collectively with direct renin inhibitors as renin-angiotensin system antagonists; beta blockers; calcium channel blockers; diuretics; and other antihypertensives
The Walgreens retrospective cohort study examined patients who filled an antihypertensive
, oral antidiabetic or antihyperlipidemic medication among those 50 years old or greater, between March and October 2014.
HOPE-3's findings will have a major influence on primary care in developed nations, where statins and antihypertensives
are inexpensive, Yusuf added.
There is currently insufficient evidence to support the use of a specific antihypertensive
agent in this setting.
However, because data about the order or introduction of the antihypertensives
were not available, we cannot support our hypothesis from the time course of the blood pressure reduction.
But finding the right antihypertensive
drug for an individual patient from among the many available medications is not necessarily a straightforward process.
medications are the most commonly prescribed class of drugs in the United States and in 2010 totaled an estimated 678 million filled prescriptions, Christopher I.
This is the first large population-based study to report such an association, and the evidence is conflicting regarding the association between antihypertensives
and fracture risk.
The overall use of antihypertensives
was not associated with breast cancer, but women who used calcium-channel blockers for more than 10 years had an elevated risk.
were not seen in that study as raising risk.
Patients themselves were asked about regularity of taking antihypertensives
(see more information below).