Physicians are cautioned not to prescribe antiemetics
over the telephone--or without first ruling out more serious illnesses in which vomiting is part of the presentation.
McCollum et al reported that propofol has significant antiemetic
activity at subhypnotic doses (8) and many anaesthesiologists use it because of this property (9).
Studies of antiemetic
agents other than ondansetron had small sample sizes, were of low methodological quality, and produced inconsistent results," the researchers explained.
25 mg) for antiemetic
prophylaxis during general anesthesia in outpatient surgery observed no significant increase in the corrected QT (QTc) interval, compared with saline (Anesthesiology 2005;102:1101-5).
was given whenever VAS was > 5.
Post-discharge nausea and vomiting is a significant issue for ambulatory patients and the most effective time to provide antiemetic
medications is of importance; however, the correct timing for use of ondansetron has not been clearly established.
Keep in mind that tegaserod does not have antiemetic
effects, and consider adding an antiemetic
agent as well, he said.
The drug was almost three times as effective as placebo for pain and nausea reduction, but not as effective as other phenothiazine antiemetics
(prochlorperazine and chlorpromazine).
At 12 weeks gestation she had lost 14% of her prepregnancy body weight and antiemetic
medications had failed.
Can we identify which antiemetic
and anesthetic agents are associated with the lowest risk of postoperative complications?
All patients received 5-HT3 receptor antagonist antiemetics
on Day 1 of all cycles.
We believe Syndros represents a viable alternative for the delivery of dronabinol and will fulfill a significant unmet need for both cancer patients undergoing chemotherapy who fail traditional antiemetics
and AIDS patients who experience anorexia associated with weight loss, said Stephen Sherman, Senior Vice President, Regulatory Affairs of Insys.
Prophylactic administration of antiemetics
does reduce incidence and suffering due to PONV and its consequences.
We also wanted to study the incidence of early or delayed vomiting, and the requirement of rescue antiemetics
, and any side effects of these.
Used in combination with a 5-HT(3) antagonist class of antiemetics
and dexamethasone, fosaprepitant dimeglumine is indicated for the prevention of acute and delayed nausea and vomiting due to highly emetogenic cancer chemotherapy.