cytotoxicity

(redirected from Antibody-dependent cellular cytotoxicity)
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Related to Antibody-dependent cellular cytotoxicity: antibody-dependent cell-mediated cytotoxicity (ADCC)
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  • noun

Words related to cytotoxicity

the degree to which something is toxic to living cells

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POTELLIGENTA Technology is designed to improve the potency and efficacy of therapeutic antibodies by enhancing antibody-dependent cellular cytotoxicity (ADCC), one of the major mechanisms of therapeutic antibodies.
Antibody-dependent cellular cytotoxicity of Coxiella burnetii-infected J774 macrophage target cells.
Seattle Genetics has previously reported that small molecule inhibitors of fucosylation can be used in vitro to produce defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity (ADCC) activity (SEA technology).
Finally, rituximab (Rituxan)-mediated antibody-dependent cellular cytotoxicity against tumour targets was improved significantly by the addition of poly(I) * poly(C12,U).
The new patent covers monoclonal antibodies having an enhanced antibody-dependent cellular cytotoxicity (ADCC) due to an improved glycosylation profile for fucose.
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