Although it is rare, people may contract anthrax disease
through natural exposures, such as contact with infected animals or contaminated animal products.
ABthrax (raxibacumab) is in late-stage development for the treatment of anthrax disease
, and the company is on track to begin the delivery in 2008 of 20,000 doses of ABthrax to the Strategic National Stockpile under a contract entered into with the United States Government in June 2006.
THE FBI was today investigating the death of a British-born journalist in the US after he was exposed to anthrax disease
at his workplace
The July 9, 2009 edition of The New England Journal of Medicine published the results of two pivotal randomized placebo-controlled studies conducted in rabbits and monkeys to evaluate the efficacy of raxibacumab, as well as the results of human safety studies, which supported the use of raxibacumab in the event of life-threatening inhalation anthrax disease
A new indication for BioThrax (Anthrax Vaccine Adsorbed) has received nod from the FDA to prevent disease after suspected or confirmed exposure to Bacillus anthracis, the bacterium that causes anthrax disease
is caused by infection with the anthrax bacteria.
anthracis bacteria (2) need for long-term dosing to achieve full protection, complicated by side effects and non-compliance (3) lack of efficacy when administered late in the anthrax disease
cycle, and (4) lack of effectiveness against multi-drug resistant or genetically engineered strains of anthrax.
In June 2006, HGS announced that the United States government exercised its option under an existing contract to purchase 20,000 doses of ABthrax for the treatment of anthrax disease
anthracis had repeat nasal swabs at 7 days postexposure and were administered a questionnaire about symptoms consistent with anthrax disease
BioThrax is the only FDA-licensed vaccine for the prevention of anthrax disease
The ClpX gene in bacterium Bacillus anthracis not only contributes to the severity of the anthrax disease
but also makes it more difficult for a patient's immune system to fight the infection.
Illnesses that were investigated and failed to fulfill criteria for the above case definitions were classified as "no apparent anthrax disease
BioThrax is the only FDA-licensed vaccine for pre-exposure protection of adults against anthrax disease