perineum

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the general region between the anus and the genital organs

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Gestational days of birth, birth weights, fetal body weight, CRL, placental weight, weight-to-length ratio, and anogenital distance were compared using analysis of variance (ANOVA).
In relation to the physical and reflex development, the pups whose mothers received propofol on the fifteenth gestational day showed a significant delay in the pinna detachment (Table 5) and an increase in the anogenital distance of the male pups (Table 6).
Eisenberg and his research team measured the anogenital distance and penile length of 117 infertile men and 56 fertile men from an andrology clinic.
Anogenital distance, while rarely studied in humans, is believed to be a marker of antiandrogenic action, with possible implications for fertility later in life.
Anogenital distance is typically longer in males than in females.
Reproductive biology expert Professor Frederick von Saal, University of Missouri-Columbia in the US, said the male hormone testosterone had a direct effect on anogenital distance, causing it to be longer in males than in females.
Pregnant rats produced male offspring with decreased prostatic and seminal vesicular weights, delayed preputial separation and transient nipple development when given finasteride at > or =30 microg/kg/day (> or =3/10 of the recommended human dose) and decreased anogenital distance when given finasteride at > or =3 microg/kg/day (> or =3/100 of the recommended human dose).
For example, anogenital distance (AGD), the distance from the anus to the genitals, can be measured from birth and is important because a) it is a well-documented index of prenatal androgen exposure in animal models; and b) in humans, it has been linked to clinically relevant measures of adult reproductive health in both sexes (Castano-Vinyals et al.
This anogenital distance is slightly, but reliably, longer in males than in females--unless those males were exposed in the womb to pollutants, such as phthalates, that can alter fetal sex-hormone production.
Additional evidence comes from the measurement of anogenital distance (AGD) in humans.
This anogenital distance is ordinarily twice as long in male rats as in females.
Anogenital distance (AGD), the distance from the anus to the genitals, is sexually dimorphic, with males having a 50-100% longer AGD than females (Hsieh et al.
She then compared levels of phthalates in the blood of 541 pregnant women with their newborn babies' anogenital distance (AGD; the distance between the anus and genitals).
Anogenital distance (AGD; distance from anus to genitals) is routinely used in animal toxicology studies and is sensitive to anti-androgenic exposure.
9) In one study, self-reported use of aspirin, acetaminophen, or ibuprofen during pregnancy was associated with cryptorchidism in some boys but not others, and experimental findings for rats indicated shorter anogenital distance with exposure to acetaminophen or aspirin.