Conclusion: Androgen insensitivity
syndrome (AIS) in its various forms is the commonest of all XY DSD.
Graham-Little-Piccardi-Lassueur syndrome associated with androgen insensitivity
syndrome (testicular feminization).
The incidence of androgen insensitivity
syndrome is estimated to be 1:20, 000-64, 000 male births and with variable phenotype expression, this syndrome can present as complete or partial forms.
TABLE 1 Causes of gynecomastia (3,4) Physiologic Neonatal Adolescent Aging-related Drug induced Antiandrogens Antibiotics Antihypertensive agents GI agents Hormones Illicit drugs Psychiatric drugs Decreased androgen production Primary (testicular) hypogonadism Secondary (central) hypogonadism Decreased androgen effect or synthesis Androgen insensitivity
syndrome 5[alpha]-Reductase deficiency 17-[beta]-Hydroxysteroid dehydrogenase deficiency Increased estrogen production Adrenal tumor Testicular tumor hCG-secreting tumor Familial aromatase excess syndrome Other Liver disease Thyrotoxicosis Obesity Renal disease Malnutrition GI, gastrointestinal; hCG, human chorionic gonadotropin.
One child with completed androgen insensitivity
syndrome and having a very small phallus with well-developed vagina had female conversion.
Histology of biopsy shows a turn to the Androgen Insensitivity
Plasma SHBG concentrations are affected by a number of different diseases, high values being found in hyperthyroidism, hypogonadism, androgen insensitivity
and hepatic cirrhosis in men.
6) An example of the former group of disorders is complete or partial androgen insensitivity
Although there are many examples of how a variation in chromosome composition and concordant anatomy can occur, one example is called androgen insensitivity
syndrome or AIS.
Mutations of the AR may result in male infertility or complete or partial androgen insensitivity
(Brockschmidt et al.
Thus, androgen insensitivity
syndrome, for example, was understood more generally as a case of male pseudohermaphroditism.
In comparison, a separate recent study found that vaginal dilation improved scores for sexual satisfaction and decreased scores for "sexual depression" in 8 women with vaginal agenesis because of androgen insensitivity
syndrome (AIS) but not in 18 women with vaginal agenesis because of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, Dr.
as a cause of infertility in otherwise normal men.
These include vaginal atresia, longitudinal septi, transverse septum, cervical agenesis, androgen insensitivity
syndrome, and intersex conditions.
Other male babies born with Androgen Insensitivity
(AI) Syndrome (testosterone is an androgen) are also worse at systemizing.