HRCT/CT and associated spirometric effects of low Libby amphibole asbestos
However, a recent review reported on the perceived strength of the literature support for the association of asbestos exposure with autoimmunity, and the strongest data was shown to be in studies of tremolite, an amphibole asbestos
, or mixtures with heavy amphibole content .
Given these similarities to amphibole asbestos
, the hypothesis of this study is that erionite will evoke autoimmune reactions similar to what has been seen from asbestos exposure.
In another study, activity-based air and surface sampling was conducted in three homes to evaluate amphibole asbestos
exposures during specific activities in attics containing VAI (Ewing et al., 2010).
As a substance of intense scientific and medical scrutiny, the use of amphibole asbestos
along with past practices and products that allowed fibres to be released into the air (like spray insulation) was blamed more so for asbestos-related illnesses.
HSE recognises that the risks to human health associated with chrysotile are lower than those associated with amphibole asbestos
(blue, brown etc) but that does not imply that chrysotile does not cause cancer.
The iron-formation also hosts amphibole asbestos
which was extensively mined in the past.
The best model for understanding asbestos-related fibrogenicity and mesothelial carcinogenicity is the very slow clearance of long, thin biopersistent fibers, of which commercial amphibole asbestos
(amosite and crocidolite), erionite, and refractory ceramic fibers are excellent examples, from respiratory compartments.
Amosite and crocidolite are the commercially valuable forms of amphibole asbestos
. Asbestos-containing material (ACM) is any material that contains more than 1% of asbestos and is of two types: friable and bonded (Occupational Safety and Health Standard, Toxic and Hazardous Substances: Asbestos, 1988; U.S.
Vermiculite ore from a mine near Libby, Montana, is known to be contaminated with amphibole asbestos
(primarily winchite, rich-terite, and tremolite), which is liberated in the mining and processing of the ore [Agency for Toxic Substances and Disease Registry (ATSDR) 2008; Meeker et al.
Effect of size-fractionation on the toxicity of amosite and Libby amphibole asbestos
. Toxicol Sci 118:420-434.
Distribution and characteristics of amphibole asbestos
fibres, measured with the light microscope, in the left lung of an insulation worker.
The report from this workshop also indicated that epidemiological and pathological data demonstrate that mesothelioma is related to amphibole asbestos
Autoantibodies from mice exposed lo Libby amphibole asbestos
bind SSA/ Ro52-enriched apoptotic blebs of murine macrophages.