[24.] Mertz H et el, Effect of Amitryptiline
on Symptoms, Sleep, and Visceral Perception in Patients With Functional Dyspepsia.
We are aware of one case report in the literature describing a 47-year-old woman who took an overdose of baclofen, amitryptiline
and alcohol and who developed features of diabetes insipidus: polyuria, low serum osmolality and high plasma osmolality which responded to desmopressin (5).
Drugs that triggered Torsades de Pointes Antibiotic agents Anti-arrhythmics Psychotropic agents Erythromycin (n=4) Sotalol (n=3) Amitryptiline
(n=1) Roxithromycin (n=2) Ibutilide (n=1) Haloperidol (n=1) Gatifloxacin (n=2) Quinidine (n=1) Fluoxetine (n=1) Clarithromycin (n=1) Amiodarone (n=1) Risperidone (n=1) Levofloxacin (n=1) Antibiotic agents Anti-histamines Erythromycin (n=4) Astemisol (n=2) Roxithromycin (n=2) Terfanidine (n=1) Gatifloxacin (n=2) Clarithromycin (n=1) Levofloxacin (n=1)
Paul Pitts took an overdose of amitryptiline
after he received "bad news" from his girlfriend while serving a seven-year sentence at Stafford Jail.
* Tricyclic antidepressants (amitryptiline
, imipramine, etc.).
The more sedating tricyclic amines (amitryptiline
[Elavil[R]]) are used to assist in initiating and maintaining sleep but must be monitored carefully due to anticholinergic side effects.
Carbamazepine (Tegretol) is the cornerstone of treatment for paroxysmal pain. Antiepileptic drugs such as gabapentin (Neurontin) and lamotrigine (Lamictal) have proved effective in treatment of paroxysmal pain.[21,36] Amitryptiline
(Elavil), clonazepam (Klonopin), diazepam (Valium), or applications of heat and cold are also useful.
True (A) or false (B)--fill in only block A or B: Amitryptiline
remains a first-line therapy of choice in DPN.
Tricyclic antidepressants (such as imipramine, amitryptiline
, and others) fell out of favor in the early 1990s, after growing evidence that they induced numerous serious side effects and were often poorly tolerated.