There are two types of arrangement for secondary structures: the alpha-helix
and beta sheets.
In one case, that of a glucocorticoid receptor protein, they found a specific spiral structure -- an alpha-helix
-- that appears to spur transcription.
5,440,013 and 5,446,128, issued on August 8 and August 29, provide protection for the more efficient, reproducible construction of conformationally restricted beta-turn, beta-bulge and alpha-helix
Studying the configuration of how calpastatin bound to the active site of the calpain complex, "we found that there was a small alpha-helix
that fit into the active site of the calpain enzyme," Greenbaum said.
These patents cover both composition of matter and method of use claims for proprietary small-molecule urazole and non-urazole beta-strands, reverse-turns, and alpha-helix