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GP is an allosteric enzyme that catalyzes the degradative phosphorolysis of glycogen to glucose 1-phosphate.
Their topics include a natural history of sensor domains in bacterial signaling systems, sensing ligands by periplasmic sensing histidine kinases with sensory pas domains, bacterial chemoreceptors as membrane-spanning allosteric enzymes, metal-dependent and metal responsive regulatory systems, and thiol-based sensory factors.
The topics covered in the subsequent chapters include characterization of enzyme activity by the equilibrium and steady-state models; reversible, irreversible, and mechanism-based (alternate and suicide inhibition) enzyme inhibition; effects of pH on enzyme reactions; mechanisms of enzyme reactions; two- and multisubstrate reactions; immobilized, interfacial, and allosteric enzymes; transient phases of enzyme reactions; and enzyme stability.