Alkenyl glycoside and alkynyl
glycosides could also be prepared by using triethylsilane instead of hydrogen as a reductant.
Apart from the typical triply dehydrogenation actions, the main feature of Glaser coupling is to cleave C-H bond, a part of alkynyl
. The process of the action can be schematically represented as
In the [sup.1]H NMR of compounds 2b, the alkynyl
proton appeared at [delta] 3.09 [C=C-H] and the methylene protons [-(C[H.sub.2])n-] appeared at [delta] 1.37-1.28 (Figure 2).
Xu, "Dehalogenative homocoupling of terminal alkynyl
bromides on Au(111): incorporation of acetylenic scaffolding into surface nanostructures," ACS Nano, vol.
Hornberger et al., "Synthesis and evaluation of aniline headgroups for alkynyl
thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors," Bioorganic and Medicinal Chemistry Letters, vol.
Williams, Metal Alkynyl
s Complexes: Synthesis and Materials, Angew.