Alkeran


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Related to Alkeran: multiple myeloma
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Synonyms for Alkeran

antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies

References in periodicals archive ?
He and other Geron researchers tested the anticancer drug melphalan (marketed as Alkeran) and an anti-telomerase agent on mice with melanoma, a lethal skin cancer.
P List (a) U List (b) Epinephrine (adrenaline) P042 Chlorambucil (Leukeran) U035 Nicotine P075 Cyclophosphamide (Cytoxan, Neosar, Procytox) U058 Nitroglycerine P081 Daunomycin (Dauorubicin, Cerubidine) U059 Physostigmine P204 Diethylstilbestrol U089 Physostigmine salicylate P188 Melphalan (Alkeran) U150 Warfarin > 0.3% P001 Mitomycin C (Mutamycin) U010 Paraldehyde U182 Phenacetin U187 Reserpine U200 Saccharin U202 Selenium sulfide U205 (e.g., dandruff shampoos) Streptozocin (Zanosar) U206 Uracil mustard U237 Warfarin (Coumadin) < 0.3% U248 (a) Representative P-listed drugs (some have other uses).
(14) The pharmacist mistook chlorambucil, the generic drug prescribed by her physician, for alkeran, the generic name for Melphalen--a substantially more powerful prescription drug that requires more careful monitoring.
* Where the method of administration is critical--for example, avoiding or treating extravasation of Alkeran.
According to the company, EVOMELA was approved by the US FDA based on its bioequivalence to the standard melphalan formulation (Alkeran) in a Phase 2 clinical study (Aljitawi et al., Bone Marrow Transplant, 2014) via the 505(b)(2) regulatory pathway.