Alkeran


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Related to Alkeran: multiple myeloma
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Synonyms for Alkeran

antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies

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He and other Geron researchers tested the anticancer drug melphalan (marketed as Alkeran) and an anti-telomerase agent on mice with melanoma, a lethal skin cancer.
Enzyme stopper combats cancers
P List (a) U List (b) Epinephrine (adrenaline) P042 Chlorambucil (Leukeran) U035 Nicotine P075 Cyclophosphamide (Cytoxan, Neosar, Procytox) U058 Nitroglycerine P081 Daunomycin (Dauorubicin, Cerubidine) U059 Physostigmine P204 Diethylstilbestrol U089 Physostigmine salicylate P188 Melphalan (Alkeran) U150 Warfarin > 0.3% P001 Mitomycin C (Mutamycin) U010 Paraldehyde U182 Phenacetin U187 Reserpine U200 Saccharin U202 Selenium sulfide U205 (e.g., dandruff shampoos) Streptozocin (Zanosar) U206 Uracil mustard U237 Warfarin (Coumadin) < 0.3% U248 (a) Representative P-listed drugs (some have other uses).
Cradle-to-cradle stewardship of drugs for minimizing their environmental disposition while promoting human health. II. Drug disposal, waste reduction, and future directions. (Green Pharmacy Mini-Monograph)
(14) The pharmacist mistook chlorambucil, the generic drug prescribed by her physician, for alkeran, the generic name for Melphalen--a substantially more powerful prescription drug that requires more careful monitoring.
Reading the Rx right is not enough: millions of Americans rely on prescribed drugs to stay healthy--and on their pharmacists to protect them from medication errors. Some courts are beginning to recognize that pharmacists must do more than fill prescriptions accurately
* Where the method of administration is critical--for example, avoiding or treating extravasation of Alkeran.
Everything you needed and wanted to know about black boxed warnings
According to the company, EVOMELA was approved by the US FDA based on its bioequivalence to the standard melphalan formulation (Alkeran) in a Phase 2 clinical study (Aljitawi et al., Bone Marrow Transplant, 2014) via the 505(b)(2) regulatory pathway.
Spectrum Pharmaceuticals wins US FDA approval for EVOMELA (melphalan) for treating multiple myeloma
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