The afferents of 48 of the 52 club-like endings were associated with axon terminals; the remaining 4 neurons demonstrated the convergence of two axon terminals arranged side-by-side into one afferent fiber.
Sobotka said that studies in kidney transplant recipients indicate that while there is some regrowth of efferent fibers with partial neurologic activity, the outbound afferent fibers have little or no ability to reconnect.
The PMC controls the descending pathways involved in the micturition reflex, activating or inhibiting the parasympathetic pathways depending on the level of activity in the afferent fibers (Andersson, 2007).
Renal denervation aims to ablate efferent sympathetic and sensory afferent fibers of the renal nerves, both of which are thought to contribute to the blood pressure-lowering effect of catheter-based renal denervation (2, 4).
Although the exact mechanism remains elusive, it has been proposed that impulses generated in lesioned peripheral nerve, posterior nerve root/ganglion, or afferent fibers pass into the spinal cord--some to higher areas to cause pain, while others into the local interneuron and motor neurons to generate involuntary movements of the toes.
A-delta fibers which are small diameter-myelinated and pain-transmitting fiber demonstrate the greatest decrease in conduction velocity in response to the cooling (29), but afferent fibers that translate the proprioceptive information from muscle spindles to the CNS are type of I[alpha] and II meaning large myelinated fiber that have fast conduction (30).