Polymorphisms in the beta2 adrenergic receptor
and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers.
NaI exposure also influenced the mRNA expression of a wide range of rhodopsin-like G-protein-coupled receptors including adrenergic receptors
in Alzheimer's disease brain: Selective increases in the cerebella of aggressive patients.
In the late 1980s, swimmers and distance runners were compared with weight lifters to evaluate the baseline catecholamine responses and adrenergic receptor
types at rest.
Although other investigators have found that leucocyte receptor expression can be used to quantify adrenergic receptors
(9,10), it is clear that there are many other post-transcriptional and cellular metabolic, factors that influence the efficacy with which adrenergic receptors
cause end-organ vascular smooth muscle vasoconstriction.
The 15 papers presented in this volume by Perez (molecular cardiology, Lerner Research Institute, Cleveland Clinic Foundation) are primarily dedicated to these approaches, broadly addressing structure-function, imaging adrenergic receptors
and their function, genetically altered mouse models, and pharmacogenetics.
Meanwhile, Connors, Crowell, and their Baltimore colleagues hypothesize that the drug terbutaline, which is usually used for asthma, leads to autism by interfering with beta 2 adrenergic receptors
, cell-membrane proteins that play a major role in brain development.
In March 2000, Synaptic began making non-exclusive licenses available to companies in need of Synaptic's portfolio of intellectual property on the alpha adrenergic receptors
for drug discovery.
Both categories of drugs produce local vasoconstriction by stimulating the adrenergic receptors
on the lamina propria of vessels.
both serotonin and noradrenaline reuptake and reduces the effects of noradrenaline on adrenergic receptors
Administration of Isoprenaline in the presence and absence of Beta1 and Beta2 adrenergic receptor
antagonists showed that hESC-derived cardiomyocytes are comparable to adult human ventricular myocytes in that Isoprenaline responses can be mediated by both Beta1 and Beta2 adrenergic receptors
The drug is the first to target a specific subtype of adrenergic receptors
(alpha-2C) in the brain, which are believed to be involved in modulation of brain functions under stressful conditions, or the "fight or flight" response.
Synaptic Pharmaceutical Corporation (Paramus, NJ; 201-261-1331) announced the granting of non-exclusive licenses covering Synaptic's alpha-1 adrenergic receptors
and benign prostatic hypertrophy patents to The R.
Recent studies suggest the noradrenergic alpha-lA adrenergic receptors
Recent evidence also suggests that [beta]adrenergic blockade, in addition to blocking the adrenergic receptors
and decreasing heart rate and blood pressure, improves cardiac efficiency [beta]-blockers have also been shown to limit plaque formation in the carotid vascular endothelium at doses that have no effect on either blood pressure or heart rate.