agonist

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Synonyms for agonist

the principal character in a work of fiction

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someone involved in a contest or battle (as in an agon)

a muscle that contracts while another relaxes

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(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

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References in periodicals archive ?
Effect of two beta adrenergic agonists and feeding duration on feedlot performance and carcass characteristics of finishing lambs Livest Sci 2011; 138:251-8.
In clinical researches performed to investigate the activity between beta adrenergic agonists as tocolytic agents, it was found that IP is more active compared to ritodrine and isoproterenol.11 However, its lack of activity towards specific b2-receptors causes major side effects characterised by tachycardia and hypotension in human obstetrics.
Some drugs such as [alpha]-2 adrenergic agonist agents or their combination administered for a prolonged period of time can produce a hypertensive syndrome, which could lead to a retinal ischemic case.
Beta 2 adrenergic agonist drugs are widely used in obstetrics as tocolytics to inhibit or slow down labour and bronchodilators, but may act as functional and behavioural teratogens when given continuously in the mid to late second or early third trimesters.
Salmeterol is a long-acting beta 2 adrenergic agonist (LABA); it works by relaxing the smooth muscles in the bronchus to improve the function of breathing.
Another combination maintenance inhaler consists of an anticholinergic medication and a short-acting beta-2 adrenergic agonist. These have proven beneficial in COPD due to the synergistic effect of anti cholinergic inhibition of bronchoconstriction and the beta-2 adrenergic agonist stimulation of bronchodilation (American Thoracic Society, 1995; National Asthma Education and Prevention Program, 1997, 2003; NIH/NHLBI/WHO Workshop Report, 2003) (see Table 1).
Vibegron is an investigational once-daily oral beta-three adrenergic agonist. In the primary efficacy analysis, once-daily vibegron met the co-primary endpoints at week 12, achieving statistical significance over placebo on both reduction in daily urge urinary incontinence episodes and reduction in daily micturitions.
Dexmedetomidine, a highly selective [alpha]2 adrenergic agonist, when used as an adjuvant to spinal Bupivacaine provides a good quality of analgesia with fewer side effects.
Phenylephrine is a sympathomimetic agent which acts primarily as an alpha adrenergic agonist. Systemically administered phenylephrine is a powerful vasoconstrictor, which can cause profound haemodynamic changes.
Treatment guidelines suggest adding a long-acting, inhaled [[beta].sub.2] adrenergic agonist rather than using a high dose of corticosteroid.
Vibegron is an investigational oral beta-3 adrenergic agonist. EMPOWUR is a randomized, double-blind placebo- and active comparator controlled clinical trial in men and women with symptoms of overactive bladder, including frequent urination, sudden urge to urinate, and urge incontinence or leakage.
Myrbetriq (mirabegron), a beta-3 adrenergic agonist, is indicated as monotherapy or in combination with the muscarinic antagonist solifenacin succinate for treating overactive bladder (OAB), added the company.
Urovant Sciences announced the publication of positive results from the international Phase 2b study of vibegron, an investigational oral beta-3 adrenergic agonist being studied for adults with symptoms of overactive bladder, or OAB.
So clonidine a selective alpha-2 adrenergic agonist is extensively evaluated as an adjuvant to intrathecal local anaesthetics.