Connor (University of Connecticut Health Center) and Meltzer (University of Massachusetts Medical School) review the pharmacodynamics, indications, dosage, metabolism, and interactions of the stimulants, antidepressants, mood stabilizers, antipsychotics, anxiolytics, and adrenergic agents sometimes prescribed to children and adolescents.
Furthermore, the antigen-induced effects in this model can be ameliorated with the current armamentarium of clinically available asthma medications, including glucocorticosteroids, [[beta].sub.2] adrenergic agents, and leukotriene antagonists (Abraham 2000).
In studies with a younger population, anticholinergic agents seem to be effective for urge incontinence, but the effect of adrenergic agents in a younger population is unclear, and has never been investigated in men.
The difference in salmeterol's pharmacodynamics is reflected in its pharmacokinetics with a slower onset and time to peak effect and a longer duration of action compared with previous adrenergic agents. The drug is a modification of the saligenin albuterol, with a long nonpolar (i.e., lipophilic) N-substituted side chain.