Downs syndrome is found to be closely linked to Acute Myelogenous Leukaemia.
As the researches have shown that chromosomal anomalies are associated with malignancies, this case of Acute Myelogenous Leukaemia in Turner Syndrome highlights the fact that more researches should be done to uncover more cases of such association and further explore if there's any difference with respect to the disease occurrence and prognosis.
AbbVie, a global biopharmaceutical company, has revealed the results from a Phase two study of investigational compound, venetoclax (ABT-199/GDC-0199), in patients with acute myelogenous leukaemia during an oral presentation at the American Society of Hematology's 56th Annual Meeting, it was reported yesterday.
The Phase 2, open-label, multicentre clinical trial was intended to evaluate the preliminary efficacy of venetoclax in 32 patients with relapsed/refractory acute myelogenous leukaemia or as frontline therapy for patients who are unfit for intensive therapy.
Early indications of efficacy are for CNS cancer, myelodysplastic syndrome, acute myelogenous leukaemia
, acute promyelocytic leukaemia, and colon cancer.