hepatitis A

Acute hepatitis A virus revealed by acalculous cholecystisis.

Increasing trend of acute hepatitis A in north India: need for identification of high-risk population for vaccination.

(1) Acute hepatitis A: elevated aminotransferase levels with peak value above 500 U/L and negative serology test results for hepatitis B and hepatitis C infections; (2) Recent acute hepatitis A: elevated aminotransferase levels with peak value below 500 U/L and either evolving S/CO (positive to borderline or negative) or resolving aminotransferase values (normal AST level); (3) Resolved acute hepatitis A: aminotransferase levels normal; (4) Indeterminate: elevated aminotransferase levels below 500 U/L; neither evolving S/CO nor resolution of abnormal aminotransferase values.

Newly reported hepatitis C was the most common cause of viral hepatitis, accounting for 53.2% of cases, followed by acute hepatitis A (19.8%), acute hepatitis E (12.2%), and newly reported hepatitis B (10.8%).

(11.) Hussain Z, Das BC, Husain SA, Murthy NS, Kar R Increasing trend of acute hepatitis A in north India: need for identification of high-risk population for vaccination.

In adults, jaundice develops in 70% of cases of acute hepatitis A (14), 33-50% of cases of acute hepatitis B (15,16), and 20-33% of cases of acute hepatitis C (17,18).

After initial studies on the clinical features of the disease and subsequent development of safe and effective vaccines in the early 1990s, research on acute hepatitis A faded away.

Liver enzyme abnormalities and cholestasis can be detected in the course of acute hepatitis A infections and rarely with the Graves' disease.

A 17-year-old male developed Guillain-Barre Syndrome (GBS) in association with acute hepatitis A infection followed by nephritic syndrome.

Clinicians should be advised that if acute hepatitis A and B have been ruled out, the potential for HEV should be considered.

In 2007, CDC was notified of a case of fulminant hepatitis A in a nontraveling household contact of an asymptomatic Ethiopian adoptee confirmed to have acute hepatitis A (immunoglobulin M [IgM] antibody to HAV [anti-HAV] positive).

International travel to regions where hepatitis A is endemic poses a substantial risk for acquiring hepatitis A, but this was reported by only ~4% of patients with acute hepatitis A in the Sentinel Counties Study.

All patients above the age of 12 years with clinical features consistent with acute hepatitis A and a positive serology for IgM HAV who developed acute liver failure were included in the study.