gout

The approval of Ilaris for acute gouty arthritis attacks in patients without appropriate treatment options provides new hope for those debilitated by this excruciating condition," said David Epstein, Division Head of Novartis Pharmaceuticals.

The patient was treated for acute gouty arthritis with oral colchicine 4 g/day and indomethacin 100 mg/day.

Therefore, it is one of the most commonly used agents in the treatment of acute gouty arthritis and pseudogout.

In the NDA, Merck is seeking indications for ARCOXIA for the treatment of osteoarthritis, rheumatoid arthritis, chronic low back pain, acute pain, dysmenorrhea (menstrual pain), acute gouty arthritis and ankylosing spondylitis.

NASDAQ: REGN) today announced that it will receive an additional potential royalty stream now that the European Commission (EC) has approved Novartis' llaris (canakinumab, ACZ885) in the treatment of patients with acute gouty arthritis who suffer frequent attacks, and whose symptoms cannot or should not be managed with current treatment options.

Novartis announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion for the use of llaris (canakinumab, ACZ885) in the treatment of patients with acute gouty arthritis who suffer frequent attacks, and whose symptoms cannot or should not be managed with current treatment options.

Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGFbeta1, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3.

This article presents the first available clinical decision rule for the diagnosis of acute gouty arthritis.

Data from efficacy studies evaluating ARCOXIA versus naproxen in the treatment of ankylosing spondylitis and ARCOXIA versus indomethacin in the treatment of acute gouty arthritis also are being presented at the annual meeting of the American College of Rheumatology.

Acute gouty arthritis typically does not result in any radiographic musculoskeletal changes; however, nonspecific inflammatory findings may be present.

PARIS -- Serum urate levels are often normal during acute gouty arthritis attacks, according to Dr.