An accurate assessment of transporter interactions must take into account the cellular permeability of the test compound under test, as this will determine the appropriate in vitro model to use (generally, only sufficiently permeable molecules will be subject to efflux unless they undergo active uptake
into the cell).
The selection of probiotics, such as lactobacilli and bifidobacteria and the active uptake
of neurochemicals, generated by bacteria in the gut and circulated through a patient's bloodstream, represents a pathway for probiotics to exert extra-intestinal effects including behavioral changes.
The uptake of inorganic waterborne Hg at gills prevents the active uptake
of sodium, which resulted in the inability of freshwater fishes to maintain salt balance with their surroundings.
into the cell occurs via organic anion transporting polypeptides.
Specific topics include active uptake
system of L-DOPA in the central nervous system, physiological release of DOPA, the possible existence of DOPA recognition sites, blood pressure regulation in lower brainstem and responses to levodopa and glutamate, neuroprotective and neurotoxic effects of L-DOPA in rat midbrain dopaminergic neurons in culture, and effect of neonatal treatment with monosodium glutamate on dopamine and DOPA neurons in the medial basal hypothalamus of rats.