In this investigation, few mothers of infants with congenital syphilis who acquired syphilis
after an initial nonreactive test were screened in the early third trimester, despite that most (80%) could be considered at increased risk for syphilis.
We here describe four cases of Chinese patients from one family and specifically focus on how they got infected with acquired syphilis
. Details of the cases are summarized in [Supplementary Table 1 [SUPPORTING:1]].
Shklar, "The oral manifestations of acquired syphilis
. A study of eighty-one cases," Oral Surgery, Oral Medicine, Oral Pathology, vol.
Newly acquired syphilis
in HIV-positive MSM was found in 7.3 cases per 1,000 patient-years (95% confidence interval, 5.2-9.9) for those who were regularly screened, versus 2.8 cases per 1,000 patient-years (95% CI, 1.8-4.0) for those who were screened annually.
(6,7) However the mother of at least one congenital syphilis case had tested negative at her first trimester screen but acquired syphilis
infection later in pregnancy from a believed-to-be monogamous relationship.
As to transmission, it can be divided into acquired syphilis
and congenital syphilis.
The treponemes are highly infectious and saprophytic treponemes can be found on mucous membranes in the mouth, genital tract and also in skin ulcers.6 Acquired syphilis
which is transmitted congenitally or sexually has primary, secondary, or tertiary stages.7 In congenital syphilis, an untreated mother with syphilis infects her unborn fetus.
Clinical standards for the screening and management of acquired syphilis
in HIV-positive adults.
Patients whose specimens are reactive to a treponemal EIA test but non-reactive to the a non-treponemal test have old, previously treated syphilis; very recently acquired syphilis
; or a false-positive treponemal EIA test result.
TEESSIDE is experiencing its worst outbreak of heterosexually acquired syphilis
since local records began.