Another explanation is the modulation of neuromuscular transmission, due to lowered number of vesicles fused with the presynaptic membrane and quantal size of
acetylcholin (ACh) per vesicle (Reid et al., 1999).
Abbreviations: ACh,
acetylcholin; AChE, acetylcholinesterase; EPSP, excitatory postsynaptic potential; GABA, gamma amino butyric acid.
The
acetylcholins were the first peptides discovered by Loewi in the 1920s, for which he received the Noble prize in 1936, and they cluster in the digestive system.