Polymorphism of the ADRB2
gene and response to inhaled beta-agonists in children with asthma: a meta-analysis.
The horse ADRB2 gene sequences were obtained from both whole genome sequencing and RNA-seq (Park et al.
The RT-PCR and qPCR analyses showed that the horse ADRB2 gene is expressed in various tissues such as skeletal muscle, kidney, thyroid, lung, appendix, colon, spinal cord, and heart (Figure 2A).
2] and asthma for any of the genotypes of GSTM1, GSTT1, GSTP1, TLR4, and ADRB2
ADRB2 is transcribed from an intronless gene on chromosome 5q32 that encodes a 413-residue protein with 7 transmembrane domains (2).
The importance of developing rapid ADRB2 screening protocols that differentiate codon 16/27 diplotypes is emphasized by the number of studies linking these genotypes to clinical and pharmacologic responses.
We observed no conclusive interaction effects for ADRB2.
KEY WORDS: ADRB2, air pollution, allergy, asthma, genetics, GSTPl, interaction, nitrogen oxides, polymorphism, TNF.