ACTH

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Related to ACTH assay: Aldosterone Assay, TSH assay
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Synonyms for ACTH

a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex

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The Nichols Advantage ACTH assay (Nichols Institute Diagnostics) uses one acridinium ester-labeled mouse monoclonal antibody that specifically binds to the C-terminal region of ACTH and one biotin-labeled goat polyclonal antibody that binds to the N-terminal region.
In the DPC IMMULITE ACTH assay (Diagnostic Products Corporation), a polystyrene bead within a test unit serves as the solid phase; the bead is coated with a monoclonal murine anti-ACTH antibody.
In the DPC ACTH assay, the analyte-antibody sandwich is formed in two separate incubations with a wash step, compared with a one-step incubation with both antibodies in the Nichols assay.
Two automated, nonisotopic ACTH assays have become available in recent years.
Comparison of two automated adrenocorticotropic hormone assays
Therefore, we studied the impact of time and temperature before plasma separation and analysis on the results of ACTH assays.
Preanalytical stability of adrenocorticotropic hormone depends on time to centrifugation rather than temperature
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