Who was the first scientist to demonstrate phenotypic differences of the ABO blood group system
Clearly, the ABO blood group system
exemplifies the fact that human blood group antigens are under active, intensive evolutionary selection pressure.
Landsteiner was a Nobel Prize winning scientist for his discovery of the ABO blood group system
. Marking this day started in 2004 by the World Health Organization (WHO) and the International Federation of the Red Cross and Red Crescent Societies (IFRCS).
The ABO blood group system
is classified based on the inherited properties of red blood cells (RBCs).
ABO blood group antigens are also found in a variety of epithelial cells; therefore, the clinical significance of the ABO blood group system
extends beyond transfusion medicine .
Schmitt-Ruth, "ABO blood group system
, age, sex, risk factors and cardiac infarction," Archives of Gerontology and Geriatrics, vol.
IHD, the most important cardiovascular disease, emerged as a major health problem in most societies in the twentieth century, affecting many people and often resulting in death or disability, and, during this period, only an effort to associate ABO blood group system
with IHD had started to evaluate ABO gene as a possible risk factor in its causation.
ABO blood group system
is comprised of two RBC antigens (A and B) and 6 different genotypes i.e.
Olsson, The ABO blood group system
revisited: a review and update", Immunohematology, 25(2):48-59(2009).
Matching for the antigens of the human ABO blood group system
is necessary when foreign cells or organs are considered for donation.
World Blood Donor Day - WBDD, celebrated on 14 June every year to commemorate the birthday of Karl Landsteiner, the Nobel Prize winner who discovered the ABO blood group system
serves to raise awareness of the need for safe blood and blood products and to thank voluntary unpaid blood donors for their life-saving gifts of blood.
The study of ABO blood group system
is of immense interest, due to its medical importance in different diseases and its role in blood transfusion, forensic pathology and its association with different diseases like duodenal ulcer (Hoffbrand and Pettit, 2006), diabetes mellitus (Garraty et al., 2000) and urinary tract infection (Rehman et al., 2005).
ABO blood group system
is genetically controlled and proportions of various ABO groups differ significantly in different populations and ethnic groups (1).
According to the WBDD website the June 14 event is not intended to replace events such as national Blood Donor Days, but provides a special opportunity for a united, global celebration on a day that has particular significance: the birthday of Karl Landsteiner, the Nobel prize winner who discovered the ABO blood group system
Allele frequencies and molecular genotyping of the ABO blood group system
in a Kuwaiti population.