ABO antibodies

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Related to ABO antibodies: Blood Types
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blood type antibodies

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ABO antibodies, however, are naturally occurring and can provide the most severe acute hemolytic episode, if matched with the wrong donor type.
This can occur with a mother's non-ABO alloantibodies or with IgG ABO antibodies for Group O mothers that have group A, B, or AB babies.
The antibodies of the ABO system are primarily IgM in nature, although some IgG and IgA antibodies may also be present The immune form of the ABO antibodies results from exposure to incompatible RBCs or other sources of ABO antigens.