5alpha-reductase activity in women with polycystic ovary syndrome.
Stimulatory effect of insulin on 5alpha-reductase type 1 (SRD5A1) expression through an Akt-dependent pathway in ovarian granulosa cells.
Clinical characterization and analysis of the SRD5A2 gene in six Korean patients with 5alpha-reductase
type 2 deficiency.
deficiency in man: an inherited form of male pseudohermaphroditism.
The effects of 5alpha-reductase
inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.
Beginning shortly after conception, human skin produces 5alpha-reductase
The association between polymorphisms in the CYP17 and 5alpha-reductase
(SRD5A2) genes and serum androgen concentrations in men.
Impaired glucose tolerance and insulin resistance are associated with increased adipose 11 beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase
The rationale for inhibiting 5alpha-reductase
isoenzymes in the prevention and treatment of prostate cancer.
We also know that testosterone is converted to dihydrotestosterone (DHT) by 5alpha-reductase
isozymes, which is present in tissues such as the prostate.
Significantly, such chemoprevention strategies are also based on 5alpha-reductase
inhibition thus reducing intraprostatic dihydrotestosterone levels.
Moreover, standard treatments for BPH symptoms, such as alpha blockers and 5alpha-reductase
inhibitors, can cause sexual dysfunction.
Are Men on 5alpha-Reductase
Inhibitors Appropriately Referred to Urology?
Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5alpha-reductase
Liao Structure-activity relationships for inhibition of human 5alpha-reductases