reductase

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  • noun

Words related to reductase

an enzyme that catalyses the biochemical reduction of some specified substance

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References in periodicals archive ?
5alpha-reductase activity in women with polycystic ovary syndrome.
The clinical importance of 5-Alpha-Reductase in human health and pathology: part 2: women, polycystic ovarian syndrome, premenstrual dysphoric disorder, hormone replacement therapy, and beyond
New mutations, hotspots, and founder effects in Brazilian patients with steroid 5alpha-reductase deficiency type 2.
Homozygous Ala65Pro Mutation with V89L Polymorphism in SRD5A2 Deficiency
Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5alpha-reductase inhibitor.
Medical management of benign prostatic hyperplasia in the light of available evidence / Mevcut kanitlar isiginda benign prostat hiperplazisinin tibbi tedavisi
The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.
Diagnosis of prostatic carcinoma after therapy: review 2007
Beginning shortly after conception, human skin produces 5alpha-reductase. Indeed, skin cells contain enzymes needed to produce every steroid hormone--and can contribute significantly to levels of circulating steroids.
The clinical importance of 5alpha-reductase in human health and pathology: Part 1: men, testosterone replacement, and stress
Inhibition of 5alpha-reductase in rat prostate reveals differential regulation of androgen-response gene expression by testosterone and dihydrotestosterone.
Effect of dutasteride in men receiving intermittent androgen ablation therapy: The AVIAS trial
Molecular characterization of 6 unrelated Italian patients with 5alpha-reductase type 2 deficiency.
Diagnosis of 5[alpha]-reductase 2 deficiency: is measurement of dihydrotestosterone essential?
Clinical usefulness of serum prostate specific antigen for the detection of prostate cancer is preserved in men receiving the dual 5alpha-reductase inhibitor dutasteride.
Federal death Panels
Impaired glucose tolerance and insulin resistance are associated with increased adipose 11 beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.
The neuroendocrine theory of aging: minimizing chronic stress to prevent the degenerative diseases of age
The association between polymorphisms in the CYP17 and 5alpha-reductase (SRD5A2) genes and serum androgen concentrations in men.
Association of SRD5A2 variants and serum androstane-3[alpha], 17[beta]-diol glucuronide concentration in Chinese elderly men
Significantly, such chemoprevention strategies are also based on 5alpha-reductase inhibition thus reducing intraprostatic dihydrotestosterone levels.
A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver
We also know that testosterone is converted to dihydrotestosterone (DHT) by 5alpha-reductase isozymes, which is present in tissues such as the prostate.
The next longevity revolution: estrogen metabolism in men
The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer.
A breakthrough in the relief of overactive bladder and urinary incontinence
Moreover, standard treatments for BPH symptoms, such as alpha blockers and 5alpha-reductase inhibitors, can cause sexual dysfunction.
Literature review & commentary
Are Men on 5alpha-Reductase Inhibitors Appropriately Referred to Urology?
The effect of dutasteride on the detection of prostate cancer: A set of meta-analyses
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