fluorouracil

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Words related to fluorouracil

an antimetabolite used to treat certain cancers

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To examine the effects of 5-fluorouracil on photoaging, two blinded dermatologists separately evaluated 3,042 baseline and follow-up photographs of participants by using the 5-point Allergan Forehead Lines Scale, the 5-point Melomental Lines Grading Scale, the 5-point Crow's Feet Grading Scale, and the 9-point Griffith's scale for wrinkling, hyperpigmentation, and yellowing.
Some promise in the treatment of keloid has been offered by 5-fluorouracil (5-FU), which is a potent inhibitor of thymidylate synthetase and interferes with pyrimidine metabolism, thus DNA synthesis is blocked.
Conclusion: Intralesional 5-Fluorouracil injection improved cosmesis of primary as well as recurrent pterygia, but did not have statistically significant effect on corneal astigmatism.
Treatment of small keloids with intralesional 5-fluorouracil alone vs intralesional triamcinolone acetonide with 5-fluorouracil.
Editor's Note: When grape seed was administered with 5-fluorouracil to cultured human colon cancer cells, the drug's ability to inhibit cancer growth was boosted by 26% in comparison to drug treatment alone.
Flow cytometry results indicated that the combination of eugenol and 5-fluorouracil increased the number of cells in the S and G2/M phases when compared to treatment with the individual compounds alone.
Cardiotoxicity of 5-fluorouracil in combination with folinic acid in patients with gastrointestinal cancer.
5-Fluorouracil (5-FU) is one of the most commonly used chemotherapeutic agents since 1970s for the systemic and palliative treatment of patients with cancers arising from the gastrointestinal tract, breast, head and neck.
The drug, 5-fluorouracil (5-RU) is used to treat cancers of the breast, ovaries, colon, stomach, pancreas and bladder.
Cetuximab in combination with 5-fluorouracil, leucovorin and irinotecan as a neoadjuvant chemotherapy in patients with initially unresectable colorectal liver metastases
ATLANTA -- The addition of docetaxel to the standard initial chemotherapy regimen of cisplatin and 5-fluorouracil has been shown to improve survival in locally advanced squamous cell carcinoma of the head and neck.
Sanofi-aventis recently announced that following a priority review of the supplemental new drug application (sNDA), the FDA has approved TAXOTERE[R] (docetaxel) Injection Concentrate in combination with cisplatin and 5-fluorouracil for the treatment of patients with advanced stomach cancer, including cancer of the gastro esophageal junction, who have not received prior chemotherapy for advanced disease.
It is believed that Eloxatin, used with 5-fluorouracil (5FU) and folinic acid (FA), offers a potential cure for patients with early stage bowel cancer.
The current study builds upon previous research showing that separate breast cancer cell lines have distinctive responses to two different chemotherapeutic agents, doxorubicin (DOX) and 5-fluorouracil (5FU).
The promising approach adds the new cancer drug called oxaliplatin (Eloxatin) to usual doses of 5-fluorouracil and leucovorin.