fluorouracil

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  • noun

Words related to fluorouracil

an antimetabolite used to treat certain cancers

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5-FU has been found to be an agent that may cause direct reversible cardiac toxicity or exacerbate the cause of myocardial dysfunction.
After demonstrating that the combined treatment reduces AKs in mice, they conducted the study of 131 patients with AKs, randomized to treatment with a cream containing 5% 5-FU and 0.
On the scalp, combination therapy reduced the number of AKs by 76%, while 5-FU alone reduced the number by only 6%.
The repaired tendons in this group were not topically treated with 5-FU *Research subgroup 2a: This group included the same 16 rabbits of subgroup 1a, but in the third digit of right hind paw, the FDP was partially divided and repaired with modified Kessler 2 core 5/0 Ethibond sutures (Johnson and Johnson, Somerville, NJ, USA) and a 6-0 Prolene (Johnson and Johnson) stitch for the circumferential epitenon repair.
5-FU injection (250 mg/10 ml) was purchased from Xudong-haipu parmaceutical company, Shanghai, China; regents for western blot and RT-PCR were purchased from Bio-Rad, USA; P53, bcl-2, bax, bid and [beta]-actin antibodies, secondary antibodies were obtained from cell signaling, MA, USA.
The inclusion criteria related to adult Pakistani patients with a definitive diagnosis of cancer and having received 5-FU and 5-FU based chemotherapy regimens during January 2002 and December 2004.
Cases of mild precordial pain with ST segment and/or T-wave changes, myocardial infarction, left ventricular failure, cardiogenic shock, ventricular and supraventricular arrhythmias, and sudden cardiac death have been reported (2-6) in >20% of patients receiving 5-FU.
Adjuvant chemotherapy including combination regimens of 5-FU is beneficial after surgery for premenopausal women with stage I (node-negative) breast cancer and for postmenopausal women with stage I (node-negative) breast cancer adjuvant tamoxifen is beneficial either alone for 5 years or in combination with chemotherapy.
The 42% response rate achieved with the administration of TEGAFIRI and the 39% response rate in patients receiving TEGAFOX are promising and comparable to those results achieved with infused 5-FU combinations.
We are enthusiastic about CoFactor's potential to enhance the efficacy and safety of 5-FU chemotherapy in the treatment of refractory breast cancer.
50] para 5-FU fueron: 3,57 (r=-0,96 p<0,005), 15,95 (r=-0,97 p<0,025) y 0,51 (r=-0,88 p=0,01) para colo-205, K562 y 3T3, respectivamente.
In the adjuvant setting, patients with stage III colon cancer (tumor-node-metastasis T1-3, N1-2 [any lymph node involvement], M0) should receive oxaliplatin with 5-fluorouracil (5-FU) and leucovorin (the FOLFOX regimen); or capecitabine (Xeloda); or 5-FU and leucovorin without oxaliplatin, Paul Engstrom, M.