Psychobiologic effects of 3,4-methylenedioxymethamphetamine
in humans: Methodological considerations and preliminary observations.
 Nonstandard abbreviations: MDMA, 3,4-methylenedioxymethamphetamine
(Ecstasy); LSD, lysergic acid diethylamide; HHMA, 3,4-dihydroxymethamphetamine; HMMA, 4-hydroxy-3-methoxymethamphetamine; HMA, 4-hydroxy-3-methoxyamphetamine; MDA, 3,4-methylenedioxyamphetamine; HHA, 3,4-dihydroxyamphetamine; MDEA, 3,4-methylenedioxy-N-ethylamphetamine; SPE, solid-phase extraction; QC, quality control; LOD, limit of detection; LOQ, limit of quantification.
 Nonstandard abbreviations: AM, amphetamine; MA, methamphetamine; MDA, 3,4-methylenedioxyamphetamine; MDMA, 3,4-methylenedioxymethamphetamine
; MDEA, 3,4-methylenedioxyethylamphetamine; DUID, driving under the influence of drugs; GC-MS, gas chromatography-mass spectrometry; S-HFBPCl, S-heptafluorobutyrylprolyl chloride; IS, internal standard; and NICI, negative-ion chemical ionization.
Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine
and N-ethyl-3,4-methylenedioxyamphetamine in rats.
Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine
(MDMA or "Ecstasy").
The designer drugs 3,4-methylenedioxyamphetamine (MDA)  3,4-methylenedioxymethamphetamine
(MDMA; ecstasy; adam), and 3,4-methylenedioxyethylamphetamine (MDEA; eve) are recreational drugs that are particularly popular among young people in the so-called "rave scene".
Eight patients, five men and three women aged 25-40 years, were recruited for a placebo-controlled, balanced, ascending dose study, in which all patients received one oral dose of 0.5 mg/g 3,4-methylenedioxymethamphetamine
(MDMA, also nown as Ecstasy) at wee 1, one oral dose of 1.5 mg/g MDMA at wee 2, and one oral dose of placebo at wee 3.
(12) In a study comparing serotonergic system damage caused by methamphetamine or 3,4-methylenedioxymethamphetamine
(MDMA ["Ecstasy"]), (13) methamphetamine had greater toxicity in the forebrain, including the septum, anterior cingulate, caudate nucleus, and nucleus accumbens.
This phenomenon has recently been well characterized for two basic drugs, cocaine and 3,4-methylenedioxymethamphetamine
(MDMA) (4, 23).
The analytical procedure was tested for interference with the following phenylpropylamine derivatives and common sympathomimetic amines: amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine
, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine
, ephedrine, pseudoephedrine, N-methylephedrine, amphetaminil, etilefrin, fencamfamine, fenethylline, fenfluramine, fenproporex, mefenorex, norfenefrine, phenylephrine, methylphenidate, diethylpropion, propylhexedrine, and prolintane.
Recreational use of 3,4-methylenedioxymethamphetamine
(MDMA; "ecstasy"), either alone or in combination with other drugs, such as alcohol and cannabis, has become increasingly popular among young people (6).
(MDMA;  "ecstasy") is an amphetamine derivative that seems to exert mixed stimulant and hallucinogenic effects (21).
The designer drugs 3,4-methylenedioxymethamphetamine
(MDMA,;  ecstasy), 3,4-methylenedioxyethylamphetamine (MDEA; eve), and 3,4-methylenedioxyamphetamine (MDA), the latter being a designer drug but also an important metabolite of both MDMA and MDEA, are all methylenedioxyamphetamine derivatives (Fig.
Hutt, entitled "Stereospecific Analysis and Enantiomeric Disposition of 3,4-Methylenedioxymethamphetamine
(Ecstasy) in Humans" (Clin Chem 1999;45:1058-69), the minimum value given for the ratio at the top of the right-hand column on page 1066 is incorrect.
(MDMA)  is a commonly used recreational drug known as "ecstasy", "E", or "Adam".