The main function of 1,25-dihydroxyvitamin D
for bone mineralisation is to maintain the calcium-phosphate product in the circulation, which allows passive mineralisation of collagen bone matrix.
3] enters the circulation and is metabolized sequentially first in the liver to 25-hydroxyvitamin D [25(OH)D] and then in the kidney to 1,25-dihydroxyvitamin D
0 mmol/L)] (a) 25-Hydroxyvitamin D 13 [micro]g/mL 30-80 [micro]g/mL 1,25-Dihydroxyvitamin D
89 ng/L 15-75 ng/L (a) Interval age adjusted for 3 years.
Hypercalcemia results from increased calcium absorption secondary to 1,25-dihydroxyvitamin D
production by sarcoid granulomas.
When the highest energy ultraviolet light, called UVB, penetrates the skin, it converts a precursor into vitamin D, which becomes 25-hydroxyvitamin D in the liver, and is then activated to 1,25-dihydroxyvitamin D
in the kidneys.
Assay of circulating 1,25-dihydroxyvitamin D
involving a novel single-cartridge extraction and purification procedure.
This study aimed to determine whether endogenous 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D
levels are related to all-cause and cardiovascular mortality.
The available data show that Sr absorption is increased by therapeutic administration of 1,25-dihydroxyvitamin D
or renal activation of 25-hydroxyvitamin D-1a-hydroxylase [14, 15].
The active form of vitamin D, 1,25-dihydroxyvitamin D
, is made in many different tissues, including colon, prostate, and breast.