zymogen

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Related to zymogen granules: Enzyme precursors
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Synonyms for zymogen

any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active

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References in periodicals archive ?
Acinic cell carcinoma shows overlapping architectural features with MASC, (3,8) but it typically shows basophilic cytoplasm containing periodic acid-Schiff-positive zymogen granules ("blue dot tumor"; Figure 2).
Periodic acid-Schiff-positive, diastase-resistant zymogen granules can usually be identified, although they may be patchy and limited (figure 4).
It has been consistently shown in various animal models that one of the first events in acute experimental pancreatitis consists of the premature activation of digestive enzymes within the acinar cell by co-segregation of zymogen granules with lysosomal enzymes, particularly cathepsin B.
These bodies are bluish pink in adjacent sections stained with hematoxylin and eosin and presumably are the zymogen granules released from secretory cells during food processing in this tissue.
Semisulcatus, with the appearance of numerous zymogen granules in the F-cells corresponding to a maximal rate of enzyme discharge into the tubule lumen.
Electrodensed zymogen granules were abundant in Oreochromis niloticus.