83%) had zidovudine
induced anaemia, 11 patients (25.
With the start of shipment of Lamivudine and Zidovudine
Tablets, the company said it further strengthens its growing ARV portfolio in the US market.
induced pure red cell aplasia: a case report.
Eighty-two percent of women had received HAART, 12% zidovudine
monotherapy, 2% dual therapy and 3% no therapy.
12) The zidovudine
uptake from April 2004 appeared steady, with little variation between the districts, although one might have expected a variation in the administration of zidovudine
between rural and urban districts, and that women in rural areas might not have been adequately covered as the result of more limited access to antenatal services.
Comment: This approval follows expiration of the patent of GlaxoSmithKline's capsule formulation of zidovudine
(Retrovir), previously the only form of zidovudine
The approval for the capsule form of the zidovudine
, which is manufactured by Aurobindo Pharma Ltd.
3] during or after delivery were offered combination antiretroviral therapy with nevirapine, zidovudine
, and lamivudine.
Roy Gulick and a multicenter team report the longest patient follow-up to date showing that the simultaneous initiation of indinavir (Crixivan), zidovudine
(Retrovir, AZT), and lamivudine (Epivir, 3TC) therapy is superior to sequential initiation (JAMA).
Nevirapine cut transmission risk during the first 18 months of life to 16 percent, compared to 26 percent transmission with zidovudine
The preferred regimen based on nonnucleoside reverse transcriptase inhibitors (NNRTIs) calls for a combination of efavirenz, lamivudine, and zidovudine
, tenofovir DF, or stavudine, except in women who are pregnant or may become pregnant.
(Retrovir) and stavudine (Zerit) both require intracellular phosphorylation by the cellular enzyme thymidine kinase.
In vivo antagonism with zidovudine
plus stavudine combination therapy.
prophylaxis and other antiretroviral and obstetric interventions and the avoidance of breast-feeding have reduced dramatically mother-infant HIV transmission in countries with adequate health-care resources [2,3].
In the groundbreaking AIDS Clinical Treatment Group (ACTG) protocol 076, zidovudine
(ZDV) was administered to mothers before birth and during labor and delivery and to the newborns for 6 weeks after birth (15).