valdecoxib


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Related to valdecoxib: rofecoxib, Parecoxib
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Synonyms for valdecoxib

a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract

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References in periodicals archive ?
Efficacy and tolerability of valdecoxib in treating the signs and symptoms of severe rheumatoid arthritis: a 12-week multicenter randomized double-blind placebo-controlled study.
Os seletivos para COX-2 sao representados pelo celecoxib, rofecoxib, valdecoxib e nimesulida e, ainda, os parcialmente seletivos para COX-2 como o meloxicam e o etodolaco.
Presurgical intravenous parecoxib sodium and follow-up oral valdecoxib for pain management after laparoscopic cholecystectomy surgery reduces opioid requirements and opioid-related adverse effects.
COX-1 inhibitors include: ibuprofen, naproxen, aspirin, indometacin, ketoprofen, and ketorolac; whereas COX-2 inhibitors include: lumiracoxib, rofecoxib, valdecoxib, etodolac, and celecoxib.
Understandably, this discovery precipitated a careful review of all NSAIDs, whether COX-1 inhibitors (including ibuprofen) or COX-2 inhibitors (celecoxib, valdecoxib, etoricoxib)--but it did not lead to greater scrutiny of acetaminophen.
However, in the years since the voluntary withdrawal of rofecoxib and valdecoxib from the market, few practitioners aside from rheumatologists prescribe selective COX-2 NSAIDs for children, according to survey results.
Parecoxib (Pfizer, Sydney, NSW) is a selective COX-2 inhibitor (5-7) and a prodrug which is rapidly metabolised to valdecoxib after parenteral administration (8-10).
The newer COX-2s have improved biochemical selectivity and include etorocoxib, valdecoxib, parecoxib and lumiracoxib (Figure 2).
Celecoxib, valdecoxib ve non selektif NSAII icin kardiyovaskuler toksisite konusunda ise kesin kanit yoktur (11,12).
Posteriormente otros representantes de esta misma familia quimica fueron retirados del mercado farmaceutico por sus efectos colaterales, entre los cuales se encuentran el parecoxib, valdecoxib y lumiracoxib.
The study suggested an increased risk of stroke with rofecoxib (Vioxx) and valdecoxib (Bextra), compared with the effects of nonselective agents (Stroke 2008;39:2037-45).
The drug samples, PAR, TAM and valdecoxib were obtained as gift samples from the Alpha Remedies Limited, Hingna, Nagpur, Technica Labs & Pharma Private Limited, Dehradun, Uttarakhand and Emcure Pharmaceuticals Pvt.
For example, such popular and widely prescribed drugs as troglitazone, cerivastatin, rofecoxib, valdecoxib, and cisapride were withdrawn from the market.
Classification of NSAIDs according to COX-selective properties COX-1 selective Non-selective COX-2 selective Indomethacin Diclofenac Celecoxib Piroxicam Naproxen Etoricoxib Lornoxicam Ibuprofen Parecoxib * Tenoxicam Nabumetone Rofecoxib ([dagger]) Ketoprofen Sulindac Valdecoxib ([dagger]) Ketorolac Lumiracoxib ([dagger]) Mefenamic acid Meloxicam * Parenteral formulation only ([dagger]) Withdrawn from the market, including South Africa.
3%) of which were launched in study period, including all four antiinflamatories of the coxib class: etoricoxib (M01AH05), lumiracoxib (M01AH06), parecoxib (M01AH04), and valdecoxib (M01AH03).