The diagnosis of acute leukemias (AL) is based on clinical features, systemic examination bone marrow aspiration and trephine
biopsy findings, immunophenotyping, cytogenetic and molecular investigations.
Bone marrow aspiration and trephine
biopsy findings were consistent with a diagnosis of severe aplastic anemia (marrow cellularity=20% for age; Figure 2a-g).
During the implant procedure, the first bone preparation burs were replaced by a trephine
of 2 mm in internal diameter and 3 mm in external diameter by 10 mm in length (trephine
Meisinger T229, Germany), in order to extract a sample of bone tissue in cylindrical shape which would be histologically analyzed later.
Free-omental grafts were confectioned using a 7-mm trephine
2) The diagnostic criteria for extramedullary plasmacytoma are an extramedullary tumour with clonal plasma cells, the absence or low levels of serum or urinary monoclonal immunoglobulin (M protein), histologically normal bone marrow and trephine
, and a normal skeletal survey.
A very high index of suspicion in patients with prolonged fever, cytopenias, and hyperferritinemia accompanied by relevant immunological, and genetic workup and bone marrow aspirate and trephine
biopsy to determine the cause of cytopenias and document hemophagocytosis enables timely diagnosis to initiate life - saving treatment.
Bone marrow aspirate and trephine
biopsy revealed normocellular marrow in which infection could not be definitively excluded.
The role of bone marrow aspiration and trephine
sample in hematological diagnostic in patients reffered to a teaching hospital in Ghana.
bone marrow trephine
biopsy: multifactorial cause of anaemia, no obvious infiltrates
9]/mL) but an otherwise unremarkable complete blood count, peripheral blood smear, and bone marrow aspirate and trephine
bone marrow biopsies in lymphoma and other neoplastic diseases.
Ganado is natural and decreasing sexual steroids (Alvarez-Nemegyei, 1998).
We reported a case of refractory classical Hodgkin lymphoma in which Hodgkin Reed-Sternberg (HRS) cells were only demonstrated in bone marrow aspirations and trephine
biopsy sections only when the disease disseminated.
Placement of a frontal trephine
allows for irrigation of the frontal recess in order to evacuate the frontal sinus in a minimally invasive manner.
Detection of the bcr/abl gene in bone marrow macrophages in CML and alterations during interferon therapy-a fluorescence in situ hybridization study on trephine