target cell

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Related to target cell: poikilocytosis, basophilic stippling
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  • noun

Words related to target cell

any cell that has a specific receptor for an antigen or antibody or hormone or drug, or is the focus of contact by a virus or phagocyte or nerve fiber etc

an abnormal red blood cell with the appearance of a dark ring surrounding a dark center

References in periodicals archive ?
When the vesicles are released by the NPCs, they adhere and are taken up by target cells.
The release of cAMP from a single MP-mediated transient increases cAMP levels in the cytosol of target cells (Fig.
With the above explanation and understanding, these are a few clinical settings in which you may see normal MCV with moderate to marked macrocytosis, target cells, and increased RDW: 1) liver disease; 2) myelodysplastic syndrome; and 3) a combined iron and folate deficiency.
Also, there is a chance that gene transfer reaches the precise target cell, but insert itself in the wrong place in the DNA sequence.
After pooling and concentrating the VCPs from several experiments, we found that levels of some target cell bioindicators were greatly reduced, but only in the case of B.
Upon delivery to the target cell, the targeting ligand binds to membrane receptors on the cell surface and the RNA-containing nanoparticle is taken into the cell by endocytosis.
This result suggests, says Klug, that the peptide bound to and blocked the oncogene in the target cell line but not in the control cells.
They label an axon's terminals with one dye and receptor molecules on the target cell with another.
By deriving our target cell types under GMP we can now accelerate our therapeutic programs to complete pre-clinical animal testing and begin taking aim at Phase I human clinical trials.
However, IL-4 needs the gamma chain to cause enzymes inside the target cell to take on chemical side groups called phosphates, they note.
Characterizing and modulating those interactions often requires the use of highly specialized protein agents, many of which must be produced within the target cell itself.
The system uses a microfluidic cartridge and immunomagnetic beads to isolate rare target cells of interest.
These reactions direct the target cells to form legs, a spinal cord, or other body structures.
Anderson's view, this should come only after animal research had demonstrated some key points: that the new gene could be put into the intended target cells and would remain there capable of functioning that the body would regulate the transplanted gene appropriately and that it would not harm the cell.