There was cross-reactivity with other sulfa antibiotics: Seven of 18 patients with prior sulfamethoxazole allergy reacted to oral challenge with sulfadiazine
, and 4 of 9 patients with prior allergy with sulfamethoxazole reacted to challenge with sulfamethazine.
Aloe versus silver sulfadiazine
creams for second-degree burns: a randomized controlled study.
Control of Pseudomonas infection in burns by silver sulfadiazine
Recent years have witnessed a resurgence in its use as a result of the HIV epidemic because sulfadiazine
paired with pyrimethamine is the treatment of choice for Toxoplasma encephalitis.
Upon the availability of primethamine and sulfadiazine
, TM-SMX was stopped on the second week of therapy and the treatment was continued with primethamine (after a loading dose of 200 mg, 100 mg/day) plus sulfadiazine
Peter Molan, Professor of Bio-Chemistry at Walkato University, New Zealand who also heads the university's Honey Research Unit has confirmed with experimental studies the effectiveness of controlling burn wounds with honey than silver sulfadiazine
Other products use soluble silver compounds, such as silver sulfadiazine
Topical applications of micronized sulfadiazine
silver were used to successfully treat all wound infections and no tubes needed to be removed due to infection.
Those containing a combination of CHG and silver sulfadiazine
and those coated with minocycline/ rifampicin have been shown to be beneficial.
With names like silver sulfadiazine
and silver nitrate, these germ-fighters save lives and speed healing.
Several examples of pharmaceutically important compounds include trimethoprim, sulfadiazine
, imatinib mesilate and capecitabine.
According to the number of cases reported, drugs are grouped in classes I to III: Class I (> 20 published reports): didanosine, asparaginase, azathioprine, valproic acid, pentamidine, mercaptopurine, oestrogen, opiates, tetracycline, steroids, trimethoprim, sulfadiazine
, furosemide; Class II (> 10 published reports): rifampin, lamivudine, octreotide, carbamazepine, acetaminophen, phenformin, interferon [alpha]2b, enalapril, hydrochlorthiazide, cisplatin, erythromycin, cyclopenthiazide; Class III (all medications reported to be associated with pancreatitis).
In this document, the FDA distinguished between (a) a product designed to control or prevent infection and to protect the patient (eg, sulfadiazine
ointment), an anti-infective product, which is a drug under section 201(g) of the act (CFR 21 (3.
Other common formulations include the topical antibiotic silver sulfadiazine
and the topical cauterizing agent silver nitrate.
1-3) Possible treatment regimens for TE include pyrimethamine plus sulfadiazine
(P+S), pyrimethamine plus clindamycin (P+C), co-trimoxazole, and atovaquone.