saquinavir


Also found in: Dictionary, Medical, Legal, Encyclopedia, Wikipedia.
Related to saquinavir: ritonavir, nelfinavir, Saquinavir mesylate
Graphic Thesaurus  🔍
Display ON
Animation ON
Legend
Synonym
Antonym
Related
  • noun

Synonyms for saquinavir

a weak protease inhibitor (trade name Invirase) used in treating HIV

Synonyms

References in periodicals archive ?
2007) CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir.
In the NIID group a larger array of protease inhibitors were used: nelfinavir, boosted lopinavir, boosted saquinavir (Table 2).
This study confirms previous observations of the influence of sex on saquinavir exposure.
10), (11) Liver functions should be monitored in all patients taking boosted lopinavir or saquinavir together with rifampicin-based TB treatment.
4 mg/264 mg with nevirapine 400 mg, followed by indinavir 1 600 mg with ritonavir 800 mg, ritonavir 600 mg with efavirenz 600 mg, and saquinavir 800 mg with efavirenz 800 mg, for both GPs and SPs.
Back then treatment was pretty much just saquinavir or indinavir with AZT or d4T (and perhaps some ddI and ritonavir thrown, just to calm your stomach) and not much else.
As a result, the options available for first-line HIV-2 ART are limited to either triple nucleoside reverse transcriptase inhibitor (NRTI) or boosted-protease inhibitor (PI)-based regimens using saquinavir (SQV), lopinavir (LPV), darunavir (DRV) or indinavir (IDV).
FDA-Approved Antiretroviral Agents Nucleoside RTIs Nonnucleoside RTIs Protease inhibitors abacavir (ABC) delavirdine (DLV) atazanavir (ATV) didanosine (ddl) efavirenz (EFZ) darunavir (DRV) emtricitabine (FTC) etravirine (ETV) fosamprenavir (Fos-APV) lamivudine (3TC) nevirapine (NVP) indinavir (IDV) stavudine (d4T) lopinavir/r (LPV/r) zidovudine (ZDV) nelfinavir (NFV) ritonavir (RTV) saquinavir (SQV) tipranavir (TPV) Nucleotide RTI Integrase inhibitor Fusion inhibitor tenofovir DF (TDF) raltegravir (RAL) enfuvirtide (T-20) CCR5 antagonist maraviroc (MVC) Notes: Six fixed-dose combinations are approved by the Food and Drug Administration.
A drug interaction between fusidic acid and a combination of ritonavir and saquinavir.
Risk factors for hepatotoxicity in HIV-1-infected patients receiving ritonavir and saquinavir with or without stavudine.
Se aprueba el saquinavir, primer inhibidor de la proteasa.
Nelfinavir (Viracept®), Ritonavir (Norvir®), and Saquinavir (Invirase®) inhibited growth of several types of cancer cells, with Nelfinavir being the most effective.
The pharmaceutical group Roche has announced that it has signed two agreements with Ethiopia and Zimbabwe enabling the free transfer of technical know-how that makes possible the local production of a generic anti-HIV/Aids drug known as saquinavir.
Garlic can reduce saquinavir blood levels by 51%, probably because it, too, is an inducer of the cytochrome P-450 system, he said.
In December the FDA approves saquinavir, the first protease inhibitor.