regulator gene


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  • noun

Synonyms for regulator gene

a gene that produces a repressor substance that inhibits an operator gene

References in periodicals archive ?
butyricum VPI1718 operon, it has been postulated that the regulator genes of the 1,3-PD operon of Clostridium sp.
This is the first major study that shows how small changes in one master regulator gene can cause a cascade of other metabolic effects in other genes," said Tim Spector of King's College London, who led the study.
Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutation, J Pediatr.
Characterization of a recurrent novel large duplication in the cystic fibrosis transmembrane conductance regulator gene.
Investigators are looking to restore the CF transmembrane regulator gene activity that is reduced in patients who have this disease.
In a phase II trial, researchers used an adeno-associated virus to deliver the cystic fibrosis transmembrane conductance regulator gene to the lung epithelium.
By analogy, what a regulator gene does depends on what other genes have promoters to which its product can bind.
The cystic fibrosis report concluded that in cystic fibrosis patients, adenoviral-vector-mediated transfer of the gene for the cystic fibrosis transmembrane conductance regulator gene did not correct defects in nasal epithelium.
Copernicus' unique, non-viral approach to deliver the Cystic Fibrosis Transmembrane Regulator gene (CFTR) to the affected airway cells of CF patients may eventually provide a long-term treatment for this disease.
s (NASDAQ: VRTX) two Phase 3 studies of the tezacaftor/ivacaftor combination treatment, a medicine in development to treat the underlying cause of cystic fibrosis (CF) in people ages 12 and older who have certain mutations in the cystic fibrosis transmembrane conductance regulator gene, the company said.
The drug has received approval for children with cystic fibrosis who have one of ten mutations in the cystic fibrosis transmembrane conductance regulator gene, G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, S549R and R117H.
3) The disease, which is a rare autosomal recessive disorder, is caused by mutations in the autoimmune regulator gene (AIRE) that has been mapped to chromosome region 21q22.