Generalised erythrodermic or generalised pustular psoriasis
(emergency referral is indicated), or acute unstable psoriasis (urgent referral may be justified).
In a patient with severe pustular psoriasis
who presented in 2001 with a significant flare that required hospitalization, infliximab (Remicade) treatment resulted in remarkable clearing (J.
Lotem M, Katzenelson V Rotem A, Hod M, Sandbank M: Impetigo herpetiformis: a variant of pustular psoriasis
or a separate entity?
CHICAGO -- Evidence is mounting that biologic therapies such as alefacept and efalizumab can successfully treat palmoplantar pustular psoriasis
You should not use Taclonex[R] Ointment or Taclonex Scalp[R] Topical Suspension if you are allergic to any of their ingredients, have thin skin (atrophy) at the treatment site, have known or suspected calcium metabolism disorders (too much or too little calcium in your blood or urine), have erythrodermic, exfoliative, or pustular psoriasis
, or have severe kidney or severe liver disease.
The proceeds of this financing provide AnaptysBio with the financial strength to potentially demonstrate efficacy of our anti-IL-33 program in severe adult asthma and peanut allergy patients, while also advancing our anti-IL-36 receptor program to proof-of-concept in generalized pustular psoriasis
," said Hamza Suria, President & CEO of AnaptysBio.
Erythroderma, arthropathy, localized and generalized forms of pustular psoriasis
are quite rare in contrast to guttat psoriasis.
PARIS -- At least one abnormal biologic liver parameter was found in 20 of 22 patients with generalized pustular psoriasis
, highlighting a previously underestimated connection between liver involvement and the disease, French researchers reported at the European Congress on Psoriasis 2004.
Umezawa Y, Ozawa A, Kawasima T et al: Therapeutic guidelines for the treatment of generalized pustular psoriasis
(GPP) based on a proposed classification of disease severity.
Many patients who suffer an attack of generalized pustular psoriasis
appear to have liver abnormalities, a finding that was previously noted only in isolated cases.
Psoriasis may be one of several types: plaque psoriasis, pustular psoriasis
, erythrodermic psoriasis, guttate psoriasis, or inverse psoriasis.
Genetic Validation Links Incidence of Generalized Pustular Psoriasis
With Abnormal IL-36 Receptor Signal Transduction
Newland MR, Weinstein A, Kerdel F: Rapid response to insiximab in severe pustular psoriasis
, von Zumbusch type.
Extensive body surface coverage with plaques, erythrodermic psoriasis, and pustular psoriasis
represent less common and more severe forms of the disease.
Clinical Efficacy and Safety of Brodalumab (KHK4827), A Fully Human Anti-Interleukin-17-Receptor A Monoclonal Antibody, in Japanese Patients With Generalized Pustular Psoriasis
and Psoriatic Erythroderma: A Phase 3, Open-Label, Long-Term Study ( 4827-004 Study), Poster 365, available to view beginning Friday, March 20, 7 a.