Almost all patients with HSP have cutaneous purpura
, and many of these patients have palpable purpura
, which is pathognomonic of a leukocytoclastic vasculitis, but palpable purpura
is not needed for diagnosis.
In a large majority of cases, purpura
fulminans manifests as a complication of an infectious process or as sepsis, mainly secondary to gram-negative organisms such as Neisseria meningitidis.
While each of these presents with areas of skin necrosis or purpura
, a thorough history can be revealing.
in childhood: treatment and prognosis.
Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura
of adults and children: report from an international working group.
Thrombotic thrombocytopenic purpura
(TTP) is a rare, life-threatening disease characterized by microvascular platelet deposition and thrombus formation with resulting microangiopathic hemolytic anemia (MAHA), thrombocytopenia is often accompanied by fever, renal failure, and neurological deficits.
None of the 60 hypertensive patients included in our study who were only on amlodipine, a calcium channel blocker, had any history suggestive of or examination findings suggestive of spontaneous bleeding or occurrence of purpura
In the case, the patient showed classic signs of HSP, including nonthrombocytopenic purpura
over his upper and lower extremities and gastrointestinal symptoms.
Tres dias despues se anadio dolor muscular generalizado y dolor abdominal por lo que fue hospitalizada, a la exploracion fisica se observo purpura
palpable en piernas, abdomen, torax y cara, que no desaparecia a la digito-presion, persistiendo con dolor abdominal y presencia de evacuaciones sanguinolentas (Figura 1).
This report provides comprehensive information on the therapeutic development for Idiopathic Thrombocytopenic Purpura
(Immune Thrombocytopenic Purpura
), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
A diagnosis of adult onset HSP was made based on the presence of nonthrombocytopenic purpura
with renal biopsy showing IgA nephropathy (Figure 1).
(HSP), also known as immunoglobulin A (IgA) vasculitis, is characterized by palpable purpura
, abdominal pain, renal disease, arthritis and/or arthralgia.
is a classic sign of one kind of bacterial meningitis.
Perilesional skin biopsies for immunofloresence revealed IgA deposition and C3 deposition, suggestive of Henoch-Schonlein Purpura
Idiopathic thrombocytopenic purpura
(ITP) is a quite prevalent autoimmune hematological disease.