The extent of macroscopic skin changes caused by puncturing was classified in two groups: barely and clearly visible.
Both glucose and cholesterol concentrations were assessed to detect whether the effect of frequent puncturing on microblood sampling would be different between small water-soluble molecules (glucose) and larger non-water-soluble particles (cholesterol).
We assumed a positive correlation between the finger puncture frequency and RF at the puncture site and a negative correlation between the finger puncture frequency and MRC at the puncture site because repetitive puncturing should produce a semi-permanent reactive hyperemia.
One to eight fingers of both hands were used for puncturing.
A poor correlation was found between finger puncture frequency and microcirculatory parameters at the puncture and control sites, indicating that frequent puncturing did not influence skin perfusion (Table 2).
This study presents the first evidence that repetitive finger puncturing in patients with long-standing insulin-dependent diabetes mellitus does not influence microcirculatory skin perfusion.
Vestal, commented, "The traditional method of puncturing
the skin with a lancet or needle creates anxiety and stress for many patients, while also presenting significant health care risks.