protease inhibitor


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Related to protease inhibitor: fusion inhibitor, Serine protease inhibitor
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Synonyms for protease inhibitor

References in periodicals archive ?
Another Kunitz type protease inhibitor from Prosopis juliflora with activity against papain, trypsin and chymotrypsin exerts insecticide effects against C.
The company plans to commence an interferon-free, all-oral combination clinical study evaluating its protease inhibitor plus NS5A inhibitor for the treatment of HCV during the second half of this year, said Michael Kishbauch, Achillion's president and CEO.
There is no doubt, though, that Prezista (plus low-dose Norvir) is a strong protease inhibitor.
The HIV protease inhibitor project is valued atEUR 64m, of which EUR 2m is a license fee due on signing of the agreement.
Shortly after approval, the price was set at $25 a day (wholesale acquisition price)--at the low end of the last three protease inhibitors approved (the ritonavir will cost extra).
Ritonavir has a potent effect on the cytochrome p450 3A4 enzymes in the liver such that when it is combined with another protease inhibitor (or any drug that is metabolized or affected by this enzyme), drug levels of the other drug are dramatically increased and the resultant lowered metabolism causes the other drug to stay in the body for a longer period.
Fifty-three percent of the women had not received any anti-HIV drug before pregnancy, and 70% had not received a protease inhibitor before pregnancy, said Dr.
Only patients' age and whether they were medically insured were associated with protease inhibitor treatment among each sexual preference group, though not all were statistically significant.
The invention is a proprietary tool that can be used to accelerate the discovery of hepatitis C virus protease inhibitors for the treatment of hepatitis C virus infection, and is broadly applicable for drug discovery against other protease enzyme targets as well.
Even though the virus cannot be found in their blood, doctors believe HIV is still in their bodies and that it would reproduce quickly if they stop taking the protease inhibitor.
In addition, all HIV-infected patients at risk for TB infection should be carefully evaluated and administered isoniazid for preventive treatment if indicated, regardless of their status for being prescribed protease inhibitor therapy.
Norvir is the first protease inhibitor to demonstrate that it extends survival," says Andre Pernet, vice president of pharmaceutical products research and development at Abbott.
com/research/162c36/victrelis_bocepre) has announced the addition of GlobalData 's new report "Victrelis (boceprevir) - First-in-Class Oral Hepatitis C Virus (HCV) Protease Inhibitor Approved in The US and Telaprevir to Follow" to their offering.
2) This study did not find a higher risk of death after a slow switch from a failing protease inhibitor.
TMC125 will be combined with TMC114, a new protease inhibitor also from Tibotec.