Novus conducted an in vitro assay combining its protease
activity was estimated by the method of Lowery .
Scientists at the Max Planck Institute of Neurobiology in Martinsried have now discovered a new serine protease
: neutrophil serine protease
4, or NSP4.
Streptomyces species that produce protease
This paper describes the protease
screening of 144 isolates of bacteria, yeasts and filamentous fungi isolated from coffee fruit.
a biotechnology company developing novel targeted covalent drugs, has demonstrated the first-ever selective irreversible inhibition of a viral protease
using a targeted covalent drug.
K11777 deactivates enzymes called cysteine proteases
, which a schistosome needs to digest proteins drawn from human blood.
The HIV protease
inhibitor project is targeted at inhibition of the HIV protease
enzyme and is in the pre-clinical research phase.
While Prezista was designed to overcome viral resistance to other protease
inhibitors, resistance to the drug itself can develop.
It has been almost 10 years since the approval of the first protease
inhibitor (Invirase) in December 1995.
We also provide a homology model for HA0 of the HPAI human isolate and show that in addition to adding basic residues, the H1 insertion likely increases accessibility to the protease
Certain commercial endo-proteases
, including Multifect Neutral, Protex 6L and Multifect P3000, and exo-proteases
, such as fungal protease
concentrate, an experimental fungal protease
#1 and experimental fungal protease
#2, yielded similar increases in soy protein solubility.
Last fall, the Food and Drug Administration (FDA) approved the protease
inhibitor, Lexiva, to help treat HIV.
inhibitors appear to be associated with increased risk of myocardial infarction in patients with HIV-1, Dr.
1) Furthermore, women who take protease
inhibitors as part of their combined drug regimen are no more likely to have a premature or very premature delivery or a low-birth-weight infant than are women who use combination therapy without these drugs, monotherapy or no therapy.