It creates innovative human therapeutics with a primary focus on controlling apoptosis, or programmed cell death
The authors conclude: "Our results prove that programmed cell death
is responsible for the regression of mouth parts in termite soldiers, and hence social caste differentiation in this species.
dependent mechanisms of cytotoxicity and programmed cell death
We have demonstrated for the first time that the simple depletion of vitamin B12 -- an essential enzyme co-factor for cell proliferation, can trigger programmed cell death
in cancer cells without exposure to toxic chemotherapeutic drugs or radiation," said Dr.
One way subverts the programmed cell death
that would otherwise prevent tumor formation, whereas the other way promotes tumor development through inflammation.
Toronto: RCG) and Canada's National Research Council (NRC) announced today the results of research indicating that Coenzyme Q10 can inhibit programmed cell death
(apoptosis) induced by a variety of stimuli in neuronal and lymphoid cells, which are targets in neurodegenerative diseases and AIDS.
In Caenorhabditis elegans, scientists discovered the phenomenon of programmed cell death
, which explains how biological development occurs in animals.
today announced the signing of a research agreement to apply their understanding of the processes of cell proliferation and programmed cell death
, or apoptosis, to the development of compounds which can regulate the growth or death of cells.
This stress response results in two changes that may be important to the role of STA-4783 in tumor cell killing in combination with taxanes: a dramatic increase in the production of Hsp70 and other heat shock and stress-related proteins, which can enhance immune-mediated killing of tumor cells, and the alteration of certain signal transduction pathways in tumor cells, which can affect cell proliferation and induce programmed cell death
, or apoptosis.
The Laureates have identified key genes regulating organ development and programmed cell death
and have shown that corresponding genes exist in higher species, including man," declared the award statement released by the Nobel Assembly at the Karolinska Institute in Sweden.