probenecid


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Related to probenecid: allopurinol
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Words related to probenecid

a uricosuric drug that reduces the level of uric acid in the blood

References in periodicals archive ?
This may be therapeutically useful: probenecid (described above) inhibits the renal secretion of penicillin, increasing its half-life and prolonging its action in the body.
Probenecid has been available for more than 50 years.
Probenecid should be used with caution in patients with a history of kidney stones and nephropathy.
A series of human sensory studies established that probenecid robustly inhibited the bitter taste of salicin, a compound that stimulates one of the target receptors.
Davies, the 2006 world junior champion, finished third in the men's F42 discus, but South African winner Fanie Lombaard has had an "adverse doping result" for probenecid, the IPC said.
Davies finished third in Christchurch in January, but South African Lombaard's adverse doping result for probenecid has seen Belgium's Gino de Keersmaeker awarded gold and Greece's Marinos Fylachtos bronze.
Among substances having UGT1A1-inhibiting activity is a uricosuric drug probenecid (77).
Stanozolol ( steroid), Nandrolone ( steroid), Probenecid ( diuretics) and methylhexaneamine ( stimulant) are the four substances for which the athletes tested positive during the period.
Pharmacokinetics and tolerability of oseltamivir combined with probenecid.
Amoxicillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis.
Adult Dose 250-500 mg PO qd for 5 d Pediatric Dose <18 years: Not recommended >18 years: Administer as in adults Contraindications Documented hypersensitivity Interactions Antacids, iron salts, and zinc salts may reduce serum levels; administer antacids 2-4 h before or after taking quinolones; cimetidine may interfere with metabolism of quinolones; levofloxacin reduces therapeutic effects of phenytoin; probenecid may increase levofloxacin serum concentrations; may increase toxicity of theophylline, caffeine, cyclosporine, and digoxin (monitor digoxin levels); may increase effects of anticoagulants (monitor PT) Pregnancy C-Safety for use during pregnancy has not been established.
Avoidance of alcohol and purine-rich foods, combined with allopurinol or probenecid pharmacotherapy, can help in managing chronic hyperuricemia.
A study with and without probenecid administration of their relationship to the state of consciousness after head injury.
pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.