preclinical phase


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Related to preclinical phase: preclinical trial, preclinical study
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  • noun

Synonyms for preclinical phase

a laboratory test of a new drug or a new invasive medical device on animal subjects

References in periodicals archive ?
10) This is consistent with the idea that an extended preclinical phase precedes AD onset.
At the conclusion of the preclinical phase the transition into the clinic can occur.
These biomarkers may eventually be used to diagnose the asymptomatic, preclinical phase of AD.
The first preclinical phase applies only in a research setting and outlines brain changes such as amyloid plaque buildup and nerve cell changes that may be present without significant symptoms in the patient.
Most of the developments are currently in the preclinical research phase, however there are already forty trials with patients underway--3 in Phase III, 24 in Phase II and 13 in Phase I--and 50 projects in the preclinical phase.
We can't begin to think about preventing this damage until we've learned more about the preclinical phase," Dr.
If these changes reflect early stage Alzheimer's disease, they suggest that Alzheimer's may have a preclinical phase that lasts for years and occurs even before the onset of mild cognitive impairment.
BioVectra's expertise includes preclinical phase I to phase III clinical trial material, active pharmaceutical ingredients, natural product extraction and purification and advanced intermediates.
There is no evidence that early screening reduces diabetic complications or that screening tests can detect diabetes during a preclinical phase.
2) The results show that the expected distribution of deals is skewed heavily to the preclinical phase (Exhibit 1).
HIV Therapeutics: Mymetics is in the preclinical phase, developing and testing peptides and other compounds that adhere to gp41 or the IL-2 receptor site without suppressing the immune system.
If five drugs make it through the preclinical phase, two survive the phase I and II clinical trials, and one passes the final phase III five-year clinical trials, the direct costs add up to $95 million.
The company is also developing a transdermal form of the drug for both pre-dialysis and dialysis HPT patients; this delivery system is in the preclinical phase of development.
The NASH project is in line with the companys updated business strategy which includes increased and accelerated efforts in moving high potential discovery projects forward with the aim of out-licensing them in the preclinical phase.