NDF, neutral detergent fibre; ATP, adenosine triphosphate; ADP, adenosine diphosphate; AMP, adenosine monophosphate; Cr, creatine; PCr, phosphocreatine
The muscular creatine and phosphocreatine
are changed into creatinine nonenzymatically at a constant rate which disperses out the cell and is excreted into urine by kidney.
The tCr signal, generated by creatine and phosphocreatine
, is influenced by the state of high-energy phosphate metabolism (Tedeschi et al.
Consequently, an exponential amplification is accomplished by repeating the RPA cycle, which is described as self-perpetuating until exhaustion of the phosphocreatine
The first studies of creatine loading phase suggest that there was a considerable increase in the concentrations of phosphocreatine
(PCr) muscle when supplemented 20 g/day for 2-6 days.
The creatine (Cr) signal includes concentrations of intracellular Cr and phosphocreatine
(PCr), providing a measure of bioenergetic metabolism as stated by Kraguljac et al.
1]H-MRS include N-acetylaspartate (NAA; a marker of neuronal integrity), choline-containing compounds (Cho; a marker of membrane turnover and glial proliferation), and creatine with phosphocreatine
(Cre; a marker of tissue energetic metabolism, usually considered an internal control).
The content of ATP, ADP, and phosphocreatine
in the SFI group was higher than those in the SA group.
Creatinine is formed by the degradation of phosphocreatine
for energy release in the skeletal muscle.
The effort is intermittent, acyclic, the power strength is predominant and the phosphocreatine
system is predominant during the attack and during the defensives actions.
Recovery metabolism of skipjack tuna, (Katsuwonus pelamis), white muscle: rapid and parallel changes of lactate and phosphocreatine
2) is a thiol-containing enzyme that catalyzes the reversible transfer of the phosphoryl group from phosphocreatine
to ADP, regenerating ATP.
Effects of exercise-induced intracellular acidosis on the phosphocreatine
recovery kinetics: a 31P MRS study in three muscle groups in humans.
The MRI-based technique requires patients to receive an injection of phosphocreatine
solution, which is visualised by an MRI, helping doctors get a clear image of what is happening inside.
Oral administration of creatine has been shown to increase the cerebral reservoir of phosphocreatine
, which can be used to produce adenosine triphosphate and potentially ameliorate the abnormal brain bioenergetics seen in depression.