These composites are mixed with autologous bone marrow which subsequently provides osteoprogenitor cells
and other growth factors.
In the NHO pathogenesis, it is proposed that non-collagen proteins play a role and that fibroblasts take over the role of osteoprogenitor cells
The presence of osteoprogenitor cells
and mesenchymal stem cells (MSCs), with the ability to differentiate into bone cells, is probably the predominant factor contributing to the increase in osteogenic activity and consequently, repair of bone injury.
It is known that the nerve growth factor has a regulatory role in neuroimmune and endocrine interaction and it has been found in periosteal osteoprogenitor cells
Skeletal unloading causes resistance of osteoprogenitor cells
to parathyroid hormone and to insulin-like growth factor-1.
The effect of TNFalpha secreted from macrophages activated by titanium particles on osteogenic activity regulated by WNT/BMP signaling in osteoprogenitor cells
The inner layer contains numerous osteoblasts and osteoprogenitor cells
and the outer layer is composed of dense collagen fibre, fibroblasts and their progenitor cells, hence the regenerative potential of the periosteum is immense.
Expression of [beta]-catenin was concentrated in the osteoprogenitor cells
that line the trabecular regions (Figure 5C,D).
Ectopic ossification is believed to occur as the result of the transformation of primitive cells of a mesenchymal origin, which are present in the connective tissue septa, into osteoprogenitor cells
Orthofix's Trinity product is an allograft of cancellous bone comprised of viable adult stem cells and osteoprogenitor cells
within the matrix and a demineralized bone component.
Effects of vitamin B12 on cell proliferation and cellular alkaline phosphatase activity in human bone marrow stromal osteoprogenitor cells
and UMR106 osteoblastic cells.
The histogenesis of ES remains controversial, and current wisdom as to the cellular origin is divided between mesenchymal cells, possibly osteoprogenitor cells
of the bone marrow, or neuroectodermal cells.