It accounted for 72% of the 326,000 details made for oral non-narcotic analgesics
during the quarter ending October 1997.
Products included in the NorthStar agreement include DuP 631, a non-opoid analgesic with potential antidepressant properties that may be useful in treating acute & chronic pain; DuP 747, a non-opoid analgesic that may be useful in post-operative pain and chronic pain, especially cancer pain; and DuP 769, an orally-active non-narcotic analgesic
for moderate to severe post-operative pain.
Coverage includes pre-analytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues concerning pain management and herbal supplements, and therapeutic drug monitoring for a range of medications: anticonvulsants, digitalis, cardioactive drugs, antidepressants, immunosuppressants, anti-cancer drugs, vancomycin and aminoglycosides, antibiotics, antiretroviral drugs, non-narcotic analgesics
, and anti-inflammatory drugs.
Combined Injectable Analgesics Market is total value of injectable products from: N02A - Narcotic Analgesics, N02B - Non-Narcotic Analgesics
, M01A - Anti-Rheumatics Non-Steroidal [Dynastat(r) only].
Women who maintained a normal body weight, engaged in 30 minutes of exercise per day, consumed a low-sodium diet, consumed alcohol in moderation, used non-narcotic analgesics
infrequently, and consumed supplemental folic acid had an 80% lower risk of developing hypertension, compared to the rest of the subjects.
Moreover, a study published at the end of July in the Journal of the American Medical Association looked at a combination of healthy lifestyle choices in regard to hypertension and found that women with six healthy lifestyle habits (having a body mass index of less than 25, a daily mean of 30 minutes of vigorous exercise, a high score on the Dietary Approaches to Stop Hypertension diet, modest alcohol intake, use of non-narcotic analgesics
less than once per week and intake of 400 meg/day or more of supplemental folic acid) resulted in a nearly 80% reduction in the risk of developing high blood pressure, which can often lead to heart attack, stroke and other chronic diseases.
Six modifiable lifestyle factors-normal BMI, daily vigorous exercise, diet, modest alcohol intake, non-narcotic analgesics
and folic acid supplementation-were all found to be independently associated with lower blood pressure.
Methadone is approved for moderate to severe pain that is not responsive to non-narcotic analgesics
, as well as for detoxification and maintenance treatment of opioid addiction.
While we won't eliminate the need for morphine in the near future, administration of safe non-narcotic analgesics
can minimize its use while at the same time improving pain relief," Sinatra suggests.